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OpenClinica vs Waystar: Which Healthcare IT Is Better in 2026?

Compare pricing, features, integrations, verified reviews, AI capabilities, security, and customer satisfaction, side by side, with no marketing spin.

OpenClinica
OpenClinica
Leads 1/9
Rating
,
Reviews
0
From
Custom

in Healthcare IT

Waystar
Waystar
Rating
,
Reviews
0
From
Custom

in Healthcare IT

Jump to scorecard Ask SIA

The Short Answer

OpenClinica vs Waystar, in 15 seconds

Choose OpenClinica if…

  • You have strict security & compliance needs

Choose Waystar if…

  • You prefer Waystar's approach and ecosystem

Head-to-Head Scorecard

How OpenClinica and Waystar score

OpenClinica leads on 1 of 9 measured dimensions.

  • Customer Rating

    Average score from verified user reviews

    Even
    OpenClinica
    No reviews
    Waystar
    No reviews

  • Review Volume

    Number of verified reviews, a proxy for adoption

    Even
    OpenClinica
    0
    Waystar
    0

  • Entry Pricing

    Lowest published starting price (free plan = lowest)

    Even
    OpenClinica
    Custom
    Waystar
    Custom

  • Free Access

    Availability of a free plan and/or free trial

    Even
    OpenClinica
    Free trial
    Waystar
    Free trial

  • Integrations

    Number of listed third-party integrations

    Even
    OpenClinica
    6
    Waystar
    6

  • Features

    Number of listed product capabilities

    Even
    OpenClinica
    0
    Waystar
    0

  • AI Features

    Capabilities mentioning AI, automation or ML

    Even
    OpenClinica
    ,
    Waystar
    ,

  • Security & Compliance

    Number of listed compliance certifications

    OpenClinica
    OpenClinica
    4
    Waystar
    3

  • Platforms & Deployment

    Supported platforms and deployment options

    Even
    OpenClinica
    4
    Waystar
    4

Feature Comparison

OpenClinica vs Waystar feature breakdown

Search or filter the full feature matrix, core features, AI, integrations, APIs, security and compliance.

OpenClinica
Waystar
Overview
User rating
,
,
Pricing model
Quote-based
Quote-based
Starting price
Custom
Custom
Free version
Free trial
Features
Key capabilities
,
,
AI features
,
,
Integrations & API
Integrations
SalesforceMicrosoft 365OracleSASAWSHL7 FHIR
EpicCernerathenahealtheClinicalWorksNextGenMeditech
Public API
Platforms
Deployment
CloudSaaS
CloudSaaS
Platforms
WebAPI
WebAPI
Mobile support
Security & Compliance
Compliance
SOC 2ISO 27001HIPAA21 CFR Part 11
HIPAASOC 2HITRUST
Vendor
Company
,
,
Verified
Founded
2006
2017
Headquarters
Waltham, Massachusetts, USA
Lehi, Utah, USA

Pricing Comparison

OpenClinica vs Waystar pricing

Entry pricing, plan tiers and the cost factors that shape total cost of ownership.

OpenClinica

Custom to start
ProfessionalCustom
  • Integrations
  • Analytics and reporting
  • Standard support
  • electronic data capture
EnterpriseCustom
  • randomization
  • Advanced security and controls
  • Everything in Professional
  • open-source edition

Waystar

Custom to start
ProfessionalCustom
  • claims management
  • Analytics and reporting
  • Integrations
  • Standard support
EnterpriseCustom
  • Everything in Professional
  • Advanced security and controls
  • denial prevention
  • Dedicated support and onboarding

Total cost of ownership factors

Free planOpenClinica Waystar
Free trial to evaluateOpenClinica Waystar
Transparent published pricingOpenClinica Waystar
Public API (build vs. buy add-ons)OpenClinica Waystar

Beyond list price, factor in implementation, training, add-ons and per-seat scaling when estimating total cost of ownership.

Pros & Cons

OpenClinica vs Waystar: strengths and trade-offs

OpenClinica

Pros

  • Free trial offered
  • Compliance: SOC 2, ISO 27001, HIPAA
  • Public API available

Cons

  • No free plan
  • Pricing is quote-based (less transparent)

Waystar

Pros

  • Free trial offered
  • Compliance: HIPAA, SOC 2, HITRUST
  • Public API available

Cons

  • No free plan
  • Pricing is quote-based (less transparent)

Buyer Fit

Who should use OpenClinica vs Waystar?

Startups

Either

Either keeps early-stage costs lowest with its entry tier.

Small businesses

Either

Either offers the most accessible pricing for lean teams.

Agencies

Either

Either connects to more tools for multi-client workflows.

Enterprises

OpenClinica

OpenClinica leads on compliance and breadth for complex needs.

Ecommerce

Either

Either integrates with more of the commerce stack.

SaaS companies

Either

Either is the more developer- and automation-friendly choice.

Integration overlap

Only in OpenClinica (6)

SalesforceMicrosoft 365OracleSASAWSHL7 FHIR

Only in Waystar (6)

EpicCernerathenahealtheClinicalWorksNextGenMeditech

Keep Exploring

Other alternatives worth considering

Similar healthcare it products buyers compare alongside OpenClinica and Waystar.

Availity

Availity

Custom
Dental Intelligence

Dental Intelligence

Custom
Epic Systems

Epic Systems

Custom
athenahealth

athenahealth

Custom
Medidata

Medidata

Custom
IQVIA

IQVIA

Custom
More OpenClinica alternatives →More Waystar alternatives →

Ask SIA which solution fits your business

SIA, Saaskart's AI buying assistant, weighs OpenClinica and Waystar against your team size, budget, integrations and compliance needs, then recommends the right fit and the questions to ask each vendor.

Get a personalised recommendation

OpenClinica vs Waystar, Frequently Asked Questions

What is the difference between OpenClinica and Waystar?

OpenClinica and Waystar are both Healthcare IT solutions. OpenClinica is rated 0.0/5 by 0 users, while Waystar is rated 0.0/5 by 0 users. The main differences lie in pricing, features, and target audience.

Which is better, OpenClinica or Waystar?

Based on user ratings, OpenClinica scores higher at 0.0/5. The best choice depends on your team size, budget, and specific requirements.

Which is cheaper, OpenClinica or Waystar?

Both products have custom pricing. We recommend contacting both vendors for a quote tailored to your team size.

Does OpenClinica or Waystar have a free plan?

Neither OpenClinica nor Waystar currently offers a free plan, but OpenClinica provides a free trial.

Can I switch from OpenClinica to Waystar?

Switching between OpenClinica and Waystar is possible. Both support data export. Check integration compatibility and plan for data migration to minimise disruption to your team.

Who should use OpenClinica vs Waystar?

OpenClinica is best suited for teams that prioritise enterprise features. Waystar works well for teams needing advanced capabilities.

Our Verdict

The bottom line on OpenClinica vs Waystar

Best Overall

Either

It's a tie balances user satisfaction and proven adoption.

Best for Startups

Either

It's a tie has the friendliest entry point for new teams.

Best for Enterprise

OpenClinica

OpenClinica leads on compliance and feature breadth.

Best Value

Either

It's a tie delivers the lowest cost to get started.

Best AI Features

Either

Comparable AI capabilities on both sides.

Highest Rated

Either

Both earn equal user ratings.

Ready to decide between OpenClinica and Waystar?

Visit OpenClinica Visit Waystar Ask SIA
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